Asymmetric total synthesis of eicosanoid
Title | Asymmetric total synthesis of eicosanoid |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Mohapatra, DK, Yellol, GS |
Journal | Arkivoc |
Issue | Part 3 |
Pagination | 144-155 |
Date Published | JAN |
Type of Article | Article |
Keywords | cyclopropanation, eicosanoid, lipoxygenase inhibitors, Ring-closing metathesis, Stereoselective |
Abstract | An asymmetric total synthesis of eicosanoid 4 starting from 2,2- dimethyl-( R)- 1,3- dioxolane-4- carbaldehyde is described. The key steps involved for the synthesis include modified Simmons-Smith cyclopropanation, stereoselective reduction, ring-closing metathesis (RCM) and Nozaki- Hiyama- Kishi coupling reaction. |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 1.177 |
Divison category:
Organic Chemistry