Synthesis of cis bis-beta-lactams via Staudinger cycloaddition reaction using C-2-symmetric 1,2-diamines
| Title | Synthesis of cis bis-beta-lactams via Staudinger cycloaddition reaction using C-2-symmetric 1,2-diamines |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Shaikh, AL, Puranik, VG, Deshmukh, ARAS |
| Journal | Tetrahedron |
| Volume | 61 |
| Issue | 9 |
| Pagination | 2441-2451 |
| Date Published | FEB |
| ISSN | 0040-4020 |
| Keywords | imines, ketenes, Staudinger cyclo-addition reaction, stereoselective synthesis |
| Abstract | An efficient stereoselective synthesis of bis-beta-lactams via cycloaddition reaction (Staudinger reaction) of ketenes with bisimines derived from C-2-symmetric 1, 2-diamines is described. The reaction provided diastereomeric mixture of meso and C-2-symmetric cis-bis-beta-lactams with higher selectivity for meso-bis-beta-lactams. (C) 2005 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tet.2005.01.031 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.645 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry
Physical and Materials Chemistry