Simplistic expedient and practical synthesis of (+/-)-alpha-lipoic acid
| Title | Simplistic expedient and practical synthesis of (+/-)-alpha-lipoic acid |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Chavan, SP, Shivsankar, K, Pasupathy, K |
| Journal | Synthesis-Stuttgart |
| Issue | 8 |
| Pagination | 1297-1300 |
| Date Published | MAY |
| Type of Article | Article |
| ISSN | 0039-7881 |
| Keywords | alpha-chloroesters, alpha-lipoic acid, Ozonolysis, Reformatsky reaction |
| Abstract | Synthesis of a-lipoic acid has been achieved by a simple sequence of reactions. The synthesis highlights the use of alpha-chloroesters in a Reformatsky reaction. The intermediate keto acid is an intermediate from which both isomers of lipoic acid can be prepared. |
| DOI | 10.1055/s-2005-861867 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.652 |
Divison category:
Organic Chemistry