NaIO4/KI/NaCl: a new reagent system for iodination of activated aromatics through in situ generation of iodine monochloride
| Title | NaIO4/KI/NaCl: a new reagent system for iodination of activated aromatics through in situ generation of iodine monochloride |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Emmanuvel, L, Shukla, RKant, Sudalai, A, Gurunath, S, Sivaram, S |
| Journal | Tetrahedron Letters |
| Volume | 47 |
| Issue | 28 |
| Pagination | 4793-4796 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Abstract | A new reagent system consisting of NaIO4/KI/NaCl in aq AcOH has been found to be effective in iodinating a variety of activated aromatic substrates via in situ-generated iodine monochloride, to furnish iodoaromatics in excellent yields. This iodination procedure has been applied successfully for a cost-effective synthesis of 3,3'-diaminobenzidine, a key intermediate for preparing proton conducting membranes for fuel cell applications, with high yield and a purity of 99.7%. (c) 2006 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2006.05.062 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Chemical Engineering & Process Development