Enantioselective synthesis of (+)-(S,S)-reboxetine

TitleEnantioselective synthesis of (+)-(S,S)-reboxetine
Publication TypeJournal Article
Year of Publication2006
AuthorsSiddiqui, SA, Narkhede, UC, Lahoti, RJ, Srinivasan, KV
JournalSynlett
Issue11
Pagination1771-1773
Date PublishedJUL
Type of ArticleArticle
ISSN0936-5214
Keywordscoupling, Dihydroxylation, Hydrogenation, reboxetine, trans-cinnamyl bromide
Abstract

An efficient enantioselective synthesis leading directly to (+)-(S,S)-reboxetine has been described from commercially available trans-cinnammyl bromide using Sharpless asymmetric dihydroxylation as the key step.

DOI10.1055/s-2006-944210
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.323
Divison category: 
Organic Chemistry