Design and synthesis of fluconazole/bile acid conjugate using click reaction
| Title | Design and synthesis of fluconazole/bile acid conjugate using click reaction |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Pore, VS, Aher, NG, Kumar, M, Shukla, PK |
| Journal | Tetrahedron |
| Volume | 62 |
| Issue | 48 |
| Pagination | 11178-11186 |
| Date Published | NOV |
| Type of Article | Article |
| ISSN | 0040-4020 |
| Keywords | 1, 2, 3-Triazole, Antifungal agent, bile acid, Click chemistry, fluconazole/bile acid conjugate |
| Abstract | Novel fluconazole/bile acid conjugates were designed and their regioselective synthesis was achieved in very high yield via Cu(I) catalyzed intermolecular 1,3-dipolar cycloaddition. These new molecules showed good antifungal activity against Candida species. (c) 2006 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tet.2006.09.021 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.654 |
Divison category:
Organic Chemistry