Convenient formal synthesis of (+/-)-paroxetine

TitleConvenient formal synthesis of (+/-)-paroxetine
Publication TypeJournal Article
Year of Publication2007
AuthorsChavan, SP, Khobragade, DA, Pathak, AB, Kalkote, UR
JournalSynthetic Communications
Volume37
Issue18
Pagination3143-3149
Date PublishedSEP
Type of ArticleArticle
ISSN0039-7911
Keywordsantidepressants, carbamate, electrophile, Heck reaction, piperidines
Abstract

A formal total synthesis of antidepressant (+/-)-paroxetine employing a solvent-free Heck reaction is disclosed.

DOI10.1080/00397910701545130
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)1.065
Divison category: 
Organic Chemistry