Efficient total synthesis of (-)-(3S,6R)-3,6-dihydroxy-10-methylundecanoic acid
| Title | Efficient total synthesis of (-)-(3S,6R)-3,6-dihydroxy-10-methylundecanoic acid |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Pandey, SKumar, Kumar, P |
| Journal | European Journal of Organic Chemistry |
| Issue | 2 |
| Pagination | 369-373 |
| Date Published | JAN |
| Type of Article | Article |
| ISSN | 1434-193X |
| Keywords | cyclic sulfate, Dihydroxylation, Grignard reaction, hydroboration-oxidation, Jacobsen's hydrolytic kinetic resolution (HKR), regio selectivity |
| Abstract | An efficient enantioselective synthesis of (-)-(3S,6R)-3,6-dihydroxy-10-methylundecanoic acid (1) from epichlorohydrin is described. The key steps include Jacobsen's HKR, Sharpless asymmetric dihydroxylation, regioselective opening of epoxide and cyclic sulfate. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007). |
| DOI | 10.1002/ejoc.200600690 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.068 |
Divison category:
Organic Chemistry