Practical formal synthesis of camptothecin

TitlePractical formal synthesis of camptothecin
Publication TypeJournal Article
Year of Publication2007
AuthorsChavan, SP, Pathak, AB, Kalkote, UR
JournalTetrahedron Letter
Volume48
Issue37
Pagination6561-6563
Date PublishedSEP
Type of ArticleArticle
ISSN0040-4039
Keywordsalkaloid, Anticancer, camptothecin, Natural product
Abstract

The synthesis of the DE ring of camptothecin using simple and inexpensive starting materials, employing an addition elimination reaction and selective esterification of an aliphatic carboxylic acid as key steps is described. (C) 2007 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2007.07.017
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.347
Divison category: 
Organic Chemistry