Total synthesis of (S)-(-)-curvularin: a ring-closing-metathesis-based construction of the macrocyclic framework
| Title | Total synthesis of (S)-(-)-curvularin: a ring-closing-metathesis-based construction of the macrocyclic framework |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Mohapatra, DK, Rahaman, H, Pal, R, Gurjar, MK |
| Journal | Synlett |
| Issue | 12 |
| Pagination | 1801-1804 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 0936-5214 |
| Keywords | curvularin, Cytotoxic, Pinnick oxidation, Ring-closing metathesis, Wittig reaction |
| Abstract | A convergent, flexible, and efficient approach to the synthesis of curvularin is described. Key step is the high-yielding macrocyclic ring formation by ring-closing metathesis (RCM) using the Grubbs second-generation catalyst. |
| DOI | 10.1055/s-2008-1078504 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Organic Chemistry