Pd(II)-mediated alkynediol spiroketalization: first total synthesis of (-)-cephalosporolide E and (+)-cephalosporolide F
| Title | Pd(II)-mediated alkynediol spiroketalization: first total synthesis of (-)-cephalosporolide E and (+)-cephalosporolide F |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Ramana, CV, Suryawanshi, SB, Gonnade, RG |
| Journal | Journal of Organic Chemistry |
| Volume | 74 |
| Issue | 7 |
| Pagination | 2842-2845 |
| Date Published | APR |
| ISSN | 0022-3263 |
| Abstract | Herein we describe a concise assembly of the central 1.6-dioxaspiro[4.4]nonane core of cephalosporolides E/F by employing a Pd-mediated alkynediol cycloisomerization and their total synthesis. On the basis of spectroscopic data and optical rotation values, the absolute configurations of cephalosporolides E/F were proposed. |
| DOI | 10.1021/jo802539z |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.002 |
Divison category:
Organic Chemistry