Total synthesis of verbalactone: an efficient, carbohydrate-based approach
| Title | Total synthesis of verbalactone: an efficient, carbohydrate-based approach |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Salunke, GB, Shivakumar, I, Gurjar, MK |
| Journal | Tetrahedron Letters |
| Volume | 50 |
| Issue | 18 |
| Pagination | 2048-2049 |
| Date Published | MAY |
| ISSN | 0040-4039 |
| Keywords | Chiral pool approach, D-Glucose, verbalactone, Yamaguchi's macrolactonization |
| Abstract | A carbohydrate-based strategy for the total synthesis of verbalactone has been described. (3R,5R)-3,5-dihydroxydecanoic acid was dimerised under Yamaguchi conditions to provide verbalactone in an overall yield of 17% starting from 3-deoxy-1,2:5,6-di-O-isopropylidine-alpha-D-glucofuranose. (c) 2009 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2009.02.062 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry