Enantioselective total synthesis of (2S,3R,4R)-D-xylo-phytosphingosine from substituted azetidin-2-one
Title | Enantioselective total synthesis of (2S,3R,4R)-D-xylo-phytosphingosine from substituted azetidin-2-one |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Pandey, G, Tiwari, DKumar |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue | 26 |
Pagination | 3296-3298 |
Date Published | JUL |
ISSN | 0040-4039 |
Keywords | beta-lactam, Enantioselective synthesis, Sphingosine, Wittig reaction |
Abstract | Enantiomerically pure (2S,3R,4R)-D-xylo phytosphingosine is synthesized in 36% overall yield in seven steps from known beta-lactam (8) derived from D-mannitol triacetonide. (C) 2009 Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.tetlet.2009.02.050 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry