Concise synthesis of (2S,3S,4S)-2-(Hydroxymethyl)pyrrolidine-3,4-diol (LAB1)

TitleConcise synthesis of (2S,3S,4S)-2-(Hydroxymethyl)pyrrolidine-3,4-diol (LAB1)
Publication TypeJournal Article
Year of Publication2010
AuthorsUpadhyay, PK, Kumar, P
JournalSynthesis-Stuttgart
Issue18
Pagination3063-3066
Date PublishedSEP
ISSN0039-7881
Keywordsalkaloid, azasugars, diastereoselectivity, Garner's aldehyde, pyrrolidine, Wittig reaction
Abstract

The synthesis of (2S,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol (LAB1) from Garner's aldehyde is described using the Sharpless asymmetric dihydroxylation as the key step.

DOI10.1055/s-0030-1258185
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.260
Divison category: 
Organic Chemistry