Regioselective monoalkylation of dimethyl alkylidenesuccinates: simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A

TitleRegioselective monoalkylation of dimethyl alkylidenesuccinates: simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A
Publication TypeJournal Article
Year of Publication2011
AuthorsKshirsagar, UA, Argade, NP
JournalSynthesis-Stuttgart
Issue11
Pagination1804-1808
Date PublishedJUN
ISSN0039-7881
Keywordsalkylations, Esters, furans, heterocycles, maleic anhydrides
Abstract

Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.

DOI10.1055/s-0030-1260013
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.466
Divison category: 
Organic Chemistry