Improved synthesis and resolution of cis- and trans-2,3-diphenyl morpholines

TitleImproved synthesis and resolution of cis- and trans-2,3-diphenyl morpholines
Publication TypeJournal Article
Year of Publication2011
AuthorsJagtap, RS, Joshi, NN
JournalTetrahedron-Asymmetry
Volume22
Issue20-22
Pagination1861-1864
Date PublishedNOV
ISSN0957-4166
Abstract

An improved procedure for the synthesis of cis- and trans-2,3-diphenyl morpholines with good overall yield is described. The stereoisomers were efficiently resolved through the corresponding diastereomeric salts using tartaric acid and (R)-mandelic acid. (C) 2011 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetasy.2011.11.004
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.652
Divison category: 
Organic Chemistry