Organocatalytic stereoselective synthesis of passifloricin A
Title | Organocatalytic stereoselective synthesis of passifloricin A |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Kumar, P, Pandey, M, Gupta, P, Dhavale, DD |
Journal | Organic & Biomolecular Chemistry |
Volume | 10 |
Issue | 9 |
Pagination | 1820-1825 |
Date Published | DEC |
Type of Article | Article |
ISSN | 1477-0520 |
Abstract | The enantioselective synthesis of passifloricin A has been achieved in high diastereomeric excess. The 1,3-polyol moiety was constructed by iterative proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes while the synthesis of lactone moiety was achieved by ring-closing metathesis (RCM). |
DOI | 10.1039/c2ob06711k |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 3.568 |
Divison category:
Organic Chemistry