Synthesis and structural characterization of homochiral homo-oligomers of cis-gamma-methoxy-substituted cis- and trans-furanoid-beta-amino acids
Title | Synthesis and structural characterization of homochiral homo-oligomers of cis-gamma-methoxy-substituted cis- and trans-furanoid-beta-amino acids |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Giri, AG, Jogdand, GF, Rajamohanan, PR, Pandey, SK, Ramana, CV |
Journal | European Journal of Organic Chemistry |
Issue | 13 |
Pagination | 2656-2663 |
Date Published | MAY |
ISSN | 1434-193X |
Keywords | Amino acids, helical structures, Oxygen heterocycles, Peptides |
Abstract | Herein we describe the synthesis of cis-/trans-3-aminotetrahydrofuran-2-carboxylic acids (cis-/trans-FAA) having a ?-methoxy group cis to the amine. The homo-oligomers of these two diastereomeric FAAs have been prepared. Preliminary investigation of their solution secondary structures revealed that they are the same as the homo-oligomers of the parent cis-/trans-FAA with the methoxy group only being a spectator substituent. |
DOI | 10.1002/ejoc.201101424 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 3.344 |
Divison category:
Central NMR Facility
Organic Chemistry