Practical and highly efficient protocol for multicomponent synthesis of beta-phosphonomalononitriles and 2-amino-4H-chromen-4-yl phosphonates using diethylamine as a novel organocatalyst
| Title | Practical and highly efficient protocol for multicomponent synthesis of beta-phosphonomalononitriles and 2-amino-4H-chromen-4-yl phosphonates using diethylamine as a novel organocatalyst |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Kulkarni, MA, Pandurangi, VR, Desai, UV, Wadgaonkar, PP |
| Journal | Comptes Rendus Chimie |
| Volume | 15 |
| Issue | 9 |
| Pagination | 745-752 |
| Date Published | SEP |
| ISSN | 1631-0748 |
| Keywords | 2-amino-4H-chromenes, beta-phosphonomalononitriles, diethylamine, multicomponent reactions, organocatalyst, Phospha-Michael reaction |
| Abstract | Diethylamine has been demonstrated for the first time to be a highly efficient organocatalyst in the solvent-free synthesis of beta-phosphonomalononitriles by a three component condensation of aldehyde, malononitrile and dialkyl phosphite at ambient temperature. The applicability of the same catalyst in the synthesis of diethyl (2-amino-3-cyano-chromene-4-yl) phosphonic acid esters has also been described. (c) 2012 Published by Elsevier Masson SAS on behalf of Academie des sciences. |
| DOI | 10.1016/j.crci.2012.07.001 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.98 |
Divison category:
Polymer Science & Engineering