Orthanilic acid-promoted reverse turn formation in peptides
| Title | Orthanilic acid-promoted reverse turn formation in peptides |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Kale, SS, Priya, G, Kotmale, AS, Gawade, RL, Puranik, VG, Rajamohanan, PR, Sanjayan, GJ |
| Journal | Chemical Communications |
| Volume | 49 |
| Issue | 22 |
| Pagination | 2222-2224 |
| Date Published | JAN |
| ISSN | 1359-7345 |
| Abstract | Orthanilic acid (2-aminobenzenesulfonic acid, (S)Ant), an aromatic beta-amino acid, has been shown to be highly useful in inducing a folded conformation in peptides. When incorporated into peptide sequences (Xaa-(S)Ant-Yaa), this rigid aromatic beta-amino acid strongly imparts a reverse-turn conformation to the peptide backbone, featuring robust 11-membered-ring hydrogen-bonding. |
| DOI | 10.1039/c3cc40522b |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.718 |
Divison category:
Center for Material Characterization (CMC)
Central NMR Facility
Organic Chemistry