Total synthesis of umuravumbolide and hyptolide through silicon-tethered ring-closing metathesis
| Title | Total synthesis of umuravumbolide and hyptolide through silicon-tethered ring-closing metathesis |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Chowdhury, PSarathi, Kumar, P |
| Journal | European Journal of Organic Chemistry |
| Volume | 2013 |
| Issue | 21 |
| Pagination | 4586-4593 |
| Date Published | JUL |
| ISSN | 1434-193X |
| Keywords | lactones, Metathesis, Silanes, synthetic methods, Total synthesis, Wittig reactions |
| Abstract | The total synthesis of umuravumbolide and hyptolide has been achieved in a efficient manner by using temporary silicon-tethered ring-closing metathesis and cross-coupling reactions as key steps. The stereogenic centres were generated by means of proline-catalysed -aminoxylation of aldehydes and Brown's asymmetric allylation method. |
| DOI | 10.1002/ejoc.201300302 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.154 |
Divison category:
Organic Chemistry