Short synthesis of (2S,3S)-3-hydroxypipecolic acid
Title | Short synthesis of (2S,3S)-3-hydroxypipecolic acid |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Chavan, SP, Harale, KR, Pawar, KP |
Journal | Tetrahedron Letters |
Volume | 54 |
Issue | 36 |
Pagination | 4851-4853 |
Date Published | SEP |
Type of Article | Article |
ISSN | 0040-4039 |
Keywords | Reductive lactamization, Selective deprotection, Wittig reaction |
Abstract | A convenient synthesis of (2S,3S)-3-hydroxypipecolic acid starting from cheap and abundant L-(+)-tartaric acid has been achieved. The strategy employs selective ester reduction and reductive lactamization as key steps. (C) 2013 Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.tetlet.2013.06.111 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.391 |
Divison category:
Organic Chemistry