Stereospecific synthetic approach towards tamiflu using the ramberg-backlund reaction from cysteine hydrochloride
| Title | Stereospecific synthetic approach towards tamiflu using the ramberg-backlund reaction from cysteine hydrochloride |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Chavan, SP, Chavan, PN, Gonnade, RG |
| Journal | RSC Advances |
| Volume | 4 |
| Issue | 107 |
| Pagination | 62281-62284 |
| Date Published | NOV |
| ISSN | 2046-2069 |
| Abstract | The stereospecific formal synthesis of Tamiflu from L-cysteine hydrochloride as the chiral source is described. The notable feature of the present strategy is the Ramberg-Backlund reaction and Sharpless-Reich protocol as the key chemical transformations to access the cyclohexene skeleton of Tamiflu. |
| DOI | 10.1039/c4ra10391b |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.84 |
Divison category:
Organic Chemistry