Croncise organocatalytic route to protected (2S, 4R)-4-hydroxyornithine and(+)-pseudohygroline
| Title | Croncise organocatalytic route to protected (2S, 4R)-4-hydroxyornithine and(+)-pseudohygroline |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Jha, V, Kumar, P |
| Journal | Synlett |
| Volume | 25 |
| Issue | 8 |
| Pagination | 1089-1092 |
| Date Published | MAY |
| ISSN | 0936-5214 |
| Keywords | aldehydes, Amination, Amino alcohols, cyclization, Enantioselectivity, Wittig reaction |
| Abstract | A practical, efficient, and organocatalytic approach to the synthesis of (2S,4R)-4-hydroxyornithine and (+)-pseudohygroline is reported using proline-catalyzed sequential alpha-aminoxylation/alpha-amination reaction and Horner-Wadsworth-Emmons olefination reaction of an aldehyde as the key step. |
| DOI | 10.1055/s-0033-1340977 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Organic Chemistry