New enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl)Propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists

TitleNew enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl)Propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists
Publication TypeJournal Article
Year of Publication2014
AuthorsMujahid, M, Kunte, SS, Muthukrishnan, M
JournalTetrahedron Letters
Volume55
Issue21
Pagination3223-3226
Date PublishedMAY
Type of ArticleArticle
ISSN0040-4039
KeywordsEEHP, Epoxide, IEHP, PPAR agonists
Abstract

A new enantioselective synthetic route to the title compounds has been developed in a simple and practical way with high enantiopurity using commercially available starting material. (C) 2014 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2014.04.021
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.347
Divison category: 
Organic Chemistry