Total synthesis and structural revision of mycalol, an anticancer natural product from the marine source
Title | Total synthesis and structural revision of mycalol, an anticancer natural product from the marine source |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Seetharamsingh, B, Rajamohanan, PR, D. Reddy, S |
Journal | Organic Letters |
Volume | 17 |
Issue | 7 |
Pagination | 1652-1655 |
Date Published | APR |
ISSN | 1523-7060 |
Abstract | The total synthesis of an anticancer (anaplastic thyroid) natural lipid mycalol has been accomplished for the first time. Synthesis of originally proposed structure necessitated the revision of structure in which the position of acetate group moved from C20 to C19 and a change in stereochemistry of the glycerol unit. |
DOI | 10.1021/acs.orglett.5b00345 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 6.732 |
Divison category:
Central NMR Facility
Organic Chemistry