N-heterocyclic-carbene-catalyzed regioselective oxidative ring-opening of epoxides with aromatic aldehydes: a facile entry to alpha-acyloxyketones
| Title | N-heterocyclic-carbene-catalyzed regioselective oxidative ring-opening of epoxides with aromatic aldehydes: a facile entry to alpha-acyloxyketones |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Reddi, RN, Gontala, A, Prasad, PK, Sudalai, A |
| Journal | Asian Journal of Organic Chemistry |
| Volume | 5 |
| Issue | 1 |
| Pagination | 48-51 |
| Date Published | JAN |
| ISSN | 2193-5807 |
| Keywords | aldehydes, epoxides, halogen oxidants, N-heterocyclic carbenes, oxygen |
| Abstract | A high-yielding synthesis of -acyloxyketones using a N-heterocyclic-carbene (NHC)-catalyzed, oxidative ring-opening of epoxides with aromatic aldehydes is described. This regioselective, oxidative process utilizes a N-bromosuccinimide (NBS)/DMSO combination as the oxidant system and Et3N as the base under mild reaction conditions. |
| DOI | 10.1002/ajoc.201500355 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.275 |
Divison category:
Chemical Engineering & Process Development