Zn(ii)-metallo-photoantibiotics: experimental and computational approach identifying a therapeutic role for antibacterial and antibiofilm applications

TitleZn(ii)-metallo-photoantibiotics: experimental and computational approach identifying a therapeutic role for antibacterial and antibiofilm applications
Publication TypeJournal Article
Year of Publication2025
AuthorsKushwaha, R, Kumari, S, Mishra, A, Upadhyay, A, Rai, A, Nayak, M, Mukherjee, S, Banerjee, S
JournalChemical Communications
Volume61
Issue56
Date PublishedJUL
Type of ArticleArticle
ISSN1359-7345
Abstract

The antibacterial profiles of curcumin-based novel Zn(ii)-metallo-photoantibiotics against E. coli and B. subtilis are reported. In silico studies indicated their ROS generation capacity and binding interaction with bacterial proteins. Therapeutic results indicated the advantages of these Zn(ii)-metallo-photoantibiotics in antibacterial photodynamic therapy.

DOI10.1039/d5cc02340h
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

4.2

Divison category: 
Organic Chemistry
Database: 
Web of Science (WoS)

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