Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes
| Title | Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Attri, P, Venkatesu, P, Kumar, A |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 10 |
| Issue | 37 |
| Pagination | 7475-7478 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Abstract | In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, alpha-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced. |
| DOI | 10.1039/c2ob26001h |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.568 |
Divison category:
Physical and Materials Chemistry