Visible-light-mediated eosin Y photoredox-catalyzed vicinal thioamination of alkynes: radical cascade annulation strategy for 2-substituted-3-sulfenylindoles
| Title | Visible-light-mediated eosin Y photoredox-catalyzed vicinal thioamination of alkynes: radical cascade annulation strategy for 2-substituted-3-sulfenylindoles |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Tambe, SD, Rohokale, RS, Kshirsagar, UA |
| Journal | European Journal of Organic Chemistry |
| Issue | 18 |
| Pagination | 2117-2121 |
| Date Published | MAY |
| Type of Article | Article |
| Abstract | An organic dye photoredox-catalyzed regiospecific radical cascade annulation strategy of 2-alkynyl-azidoarenes to generate 3-sulfenylindoles via vicinal thioamination of alkynes at room temperature, mediated by visible light, was developed. The method requires mild conditions, including visible light as a traceless green energy source, room temperature, eosin Y organic dye as a photoredox catalyst, ambient air as oxidant, and easily available starting materials to provide a green, efficient, metal- and strong-oxidant-free synthesis of 3-sulfenylindoles with broad substrate scope through vicinal thioamination of alkynes. |
| DOI | 10.1002/ejoc.201800287 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.834 |
Divison category:
Organic Chemistry