Visible-light-mediated eosin Y photoredox-catalyzed vicinal thioamination of alkynes: radical cascade annulation strategy for 2-substituted-3-sulfenylindoles

TitleVisible-light-mediated eosin Y photoredox-catalyzed vicinal thioamination of alkynes: radical cascade annulation strategy for 2-substituted-3-sulfenylindoles
Publication TypeJournal Article
Year of Publication2018
AuthorsTambe, SD, Rohokale, RS, Kshirsagar, UA
JournalEuropean Journal of Organic Chemistry
Issue18
Pagination2117-2121
Date PublishedMAY
Type of ArticleArticle
AbstractAn organic dye photoredox-catalyzed regiospecific radical cascade annulation strategy of 2-alkynyl-azidoarenes to generate 3-sulfenylindoles via vicinal thioamination of alkynes at room temperature, mediated by visible light, was developed. The method requires mild conditions, including visible light as a traceless green energy source, room temperature, eosin Y organic dye as a photoredox catalyst, ambient air as oxidant, and easily available starting materials to provide a green, efficient, metal- and strong-oxidant-free synthesis of 3-sulfenylindoles with broad substrate scope through vicinal thioamination of alkynes.
DOI10.1002/ejoc.201800287
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.834
Divison category: 
Organic Chemistry

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