Tri-tert-butanolamine as an organic promoter in nucleophilic fluorination
| Title | Tri-tert-butanolamine as an organic promoter in nucleophilic fluorination |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Shinde, SS, Khonde, N, Kumar, P |
| Journal | ChemistrySelect |
| Volume | 2 |
| Issue | 1 |
| Pagination | 118-122 |
| Date Published | JAN |
| Type of Article | Article |
| Abstract | Tri-tert-butanol amine acts as promoter with alkali metal salts in the nucleophilic fluorination of alkylsulfonates. It significantly enhances the reactivity of alkali metal salts with minimum formation of side-products (alkene, ether, and alcohol) com-pared to other catalysts in fluorination reaction. The synergism of tert-alcohol and amine moiety plays a pivotal role in fluorination. |
| DOI | 10.1002/slct.201601735 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.505 |
Divison category:
Organic Chemistry