Transition-metal-free multicomponent reactions involving arynes, N-heterocycles, and isatins

TitleTransition-metal-free multicomponent reactions involving arynes, N-heterocycles, and isatins
Publication TypeJournal Article
Year of Publication2013
AuthorsBhunia, A, Roy, T, Pachfule, P, Rajamohanan, PR, Biju, AT
JournalAngewandte Chemie-International Edition
Volume52
Issue38
Pagination10040–10043
Date PublishedAUG
Abstract

Mix and match: With isoquinoline as the nucleophilic trigger, multicomponent reactions afforded spirooxazino isoquinoline derivatives, proceeding through 1,4-dipolar intermediates. The use of pyridine as a nucleophile furnished indolin-2-one derivatives, with the reaction likely proceeding through a pyridylidene intermediate.

DOI10.1002/anie.201304278
Funding Agency

Council of Scientific & Industrial Research (CSIR) - India

Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)11.336
Divison category: 
Central NMR Facility
Organic Chemistry
Physical and Materials Chemistry