Transition metal, azide, and oxidant-free homo- and heterocoupling of ambiphilic tosylhydrazones to the regioselective triazoles and pyrazoles
| Title | Transition metal, azide, and oxidant-free homo- and heterocoupling of ambiphilic tosylhydrazones to the regioselective triazoles and pyrazoles |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Panda, S, Maity, P, Manna, D |
| Journal | Organic Letters |
| Volume | 19 |
| Issue | 7 |
| Pagination | 1534-1537 |
| Date Published | APR |
| Type of Article | Article |
| Abstract | With N-tosylhydrazone as an ambiphilic reagent, an unprecedented cyclization reaction of two identical or different tosylhydrazones has been developed to access various 4,5-disubstituted-2H-triazoles under transition metal, azide, and oxidant-free conditions. A mechanistic.rationalization study led to the identification of several electronically diverse unsaturated systems for regioselective synthesis of 1- and 2-substituted 1,2,3-triazoles and pyrazoles. |
| DOI | 10.1021/acs.orglett.7b00313 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.732 |
Divison category:
Organic Chemistry