Total synthesis of tropinone using 1,3-dipolar cycloaddition of cyclic azomethine ylide and phenyl vinyl sulfone as the key step
| Title | Total synthesis of tropinone using 1,3-dipolar cycloaddition of cyclic azomethine ylide and phenyl vinyl sulfone as the key step |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Laha, JK |
| Journal | Chemistry of Natural Compounds |
| Volume | 46 |
| Issue | 2 |
| Pagination | 254-256 |
| Date Published | MAY |
| ISSN | 0009-3130 |
| Keywords | 1, 3-dipolar cycloaddition, cyclic azomethine ylide, phenyl vinyl sulfone, tropane alkaloids, tropinone |
| Abstract | Total synthesis of tropinone from the readily available piperidone 2 is described. The rapid assembly of the tropane skeleton was achieved by 1,3-dipolar cycloaddition of cyclic azomethine ylide 3 to phenyl vinyl sulfone. |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 0.693 |
Divison category:
Organic Chemistry