Total synthesis of (-)-radicamine B

TitleTotal synthesis of (-)-radicamine B
Publication TypeJournal Article
Year of Publication2006
AuthorsGurjar, MK, Borhade, RG, Puranik, VG, Ramana, CV
JournalTetrahedron Letters
Volume47
Issue39
Pagination6979-6981
Date PublishedSEP
Type of ArticleArticle
ISSN0040-4039
Keywordscodonopsinine, Cyclic nitrone, Grignard addition, polyhydroxy pyrrolidine alkaloids, radicamine B
Abstract

The synthesis of a chiral cyclic nitrone with L-arabino configuration and its application in the total synthesis of radicamine B is reported. An agreement in the spectral data with natural radicamine B but specific rotation with an opposite sign warranted a revision of the absolute configuration of radicamine B. (c) 2006 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2006.07.120
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.347
Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry
Physical and Materials Chemistry