Total synthesis of the putative structure of xylarinol B

TitleTotal synthesis of the putative structure of xylarinol B
Publication TypeJournal Article
Year of Publication2014
AuthorsMore, AA, Ramana, CV
JournalChemistry-An Asian Journal
Volume9
Issue6
Pagination1557-1562
Date PublishedJUN
ISSN1861-4728
KeywordsChiral pool, cobalt, Natural products, structure elucidation, Total synthesis
Abstract

The total synthesis of the putative structure of xylarinolB is described and the need to revise its structure is demonstrated. The central benzoxepine skeleton was constructed by employing a cobalt-mediated bimolecular [2+2+2] Reppe-Vollhardt alkyne cycloaddition reaction.

DOI10.1002/asia.201301647
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)4.92
Divison category: 
Organic Chemistry