Total synthesis of pulchellalactam via an RCM strategy

TitleTotal synthesis of pulchellalactam via an RCM strategy
Publication TypeJournal Article
Year of Publication2007
AuthorsChavan, SP, Pathak, AB, Dhawane, AN, Kalkote, UR
JournalSynthetic Communications
Volume37
Issue7-9
Pagination1503-1510
Date PublishedMAY
Type of ArticleArticle
ISSN0039-7911
Keywordsalkaloid, Natural products, pulchellalactam, RCM, Total synthesis
Abstract

Total synthesis of (Z) pulchellalactam, a CD protein tyrosine phosphatase inhibitor, from commercially available methallyl chloride employing ring-closure metathesis (RCM) as a key step is described.

DOI10.1080/00397910701229131
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)1.065
Divison category: 
Organic Chemistry