Total synthesis of (+)-petromyroxol via tandem alpha-aminoxylation-allylation and asymmetric dihydroxylation-S(N)2 cyclization approach
| Title | Total synthesis of (+)-petromyroxol via tandem alpha-aminoxylation-allylation and asymmetric dihydroxylation-S(N)2 cyclization approach |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Nookaraju, U, Kumar, P |
| Journal | RSC Advances |
| Volume | 5 |
| Issue | 78 |
| Pagination | 63311-63317 |
| Date Published | JUL |
| ISSN | 2046-2069 |
| Abstract | The total synthesis of (+)-petromyroxol, a tetrahydrofuran (THF)-diol fatty acid, isolated from sea lamprey larvae (Petromyzon marinus) is reported. The present synthesis employs a tandem alpha-aminoxylationallylation, cross metathesis and tandem asymmetric dihydroxylation-S(N)2 cyclization as key steps. |
| DOI | 10.1039/c5ra10405j |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.289 |
Divison category:
Organic Chemistry