Total synthesis of naturally occurring cephalosporolides E/F

TitleTotal synthesis of naturally occurring cephalosporolides E/F
Publication TypeJournal Article
Year of Publication2014
AuthorsKona, CNaidu, Ramana, CV
JournalTetrahedron
Volume70
Issue23
Pagination3653-3656
Date PublishedJUN
ISSN0040-4020
KeywordsAlkynetetrol, Cephalosporolide, Epoxide-alkyne coupling, Gold catalysis, Spiroketalization
Abstract

A modular total synthesis of cephalosporolides E/F featuring sequential epoxide-alkyne coupling and subsequent highly regioselective gold catalyzed alkynolcycloisomerizatio of the resulting alkynetetrol to construct the central spiroketal core has been documented. (C) 2014 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tet.2014.04.026
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.68
Divison category: 
Organic Chemistry