Total synthesis of the natural product EBC-329

TitleTotal synthesis of the natural product EBC-329
Publication TypeJournal Article
Year of Publication2015
AuthorsThombal, RS, Jadhav, VH
JournalOrganic & Biomolecular Chemistry
Volume13
Issue36
Pagination9485-9491
Date PublishedJUL
ISSN1477-0520
Abstract

The first total synthesis of an anti-leukemic diterpene natural product EBC-329 (1) has been accomplished starting from readily available 6,6-dimethyl-3-oxabicyclo[3.1.0] hexane-2,4-dione (7). An efficient and general approach has been reported for the synthesis of EBC-329 in 13 steps with an overall yield of 10%.

DOI10.1039/c5ob01276g
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)3.559
Divison category: 
Organic Chemistry