Total synthesis of (+)-isolaurepan
| Title | Total synthesis of (+)-isolaurepan |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Tripathi, D, Kumar, P |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue | 49 |
| Pagination | 7012-7014 |
| Date Published | DEC |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | Cis-selective cyclization, Cyclic ethers, Isolaurepan, Oxepanes, Oxidative resolution of secondary alcohols |
| Abstract | A versatile and efficient method for the enantioselective synthesis of 2,7-cis-disubstituted oxepane 1c, (+)-isolaurepan, using oxidative resolution of a secondary alcohol and highly diastereoselective Et(3)SiH/TMSOTf-promoted reductive cyclization of a hydroxy ketone is described. (C) 2008 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2008.09.134 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry