Total synthesis of (+)-camptothecin via an intramolecular palladium-catalyzed cyclization strategy

TitleTotal synthesis of (+)-camptothecin via an intramolecular palladium-catalyzed cyclization strategy
Publication TypeJournal Article
Year of Publication2007
AuthorsChavan, SP, Pathak, AB, Kalkote, UR
JournalSynlett
Issue17
Pagination2635-2638
Date PublishedOCT
Type of ArticleArticle
ISSN0936-5214
Keywordsalkaloids, antitumor, cyclizations, Natural products, Palladium
Abstract

The novel cascade intramolecular Pd-catalyzed cyclization followed by aromatization for the construction Of D ring of (+)-camptothecin as a key step is demonstrated.

DOI10.1055/s-2007-991054
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.323
Divison category: 
Organic Chemistry