Total synthesis and structural revision of mycalol, an anticancer natural product from the marine source

TitleTotal synthesis and structural revision of mycalol, an anticancer natural product from the marine source
Publication TypeJournal Article
Year of Publication2015
AuthorsSeetharamsingh, B, Rajamohanan, PR, D. Reddy, S
JournalOrganic Letters
Volume17
Issue7
Pagination1652-1655
Date PublishedAPR
ISSN1523-7060
Abstract

The total synthesis of an anticancer (anaplastic thyroid) natural lipid mycalol has been accomplished for the first time. Synthesis of originally proposed structure necessitated the revision of structure in which the position of acetate group moved from C20 to C19 and a change in stereochemistry of the glycerol unit.

DOI10.1021/acs.orglett.5b00345
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)6.732
Divison category: 
Central NMR Facility
Organic Chemistry