Total synthesis of (±)-streptoglyceride A and of putative (±)-streptoglyceride C
| Title | Total synthesis of (±)-streptoglyceride A and of putative (±)-streptoglyceride C |
| Publication Type | Journal Article |
| Year of Publication | 2025 |
| Authors | Khobragade, VR, Ramana, CV |
| Journal | Organic Letters |
| Volume | 27 |
| Issue | 23 |
| Pagination | 5931-5935 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 1523-7060 |
| Abstract | The first total synthesis of (+/-)-Streptoglyceride A-one of the early members of this family to be isolated-has been accomplished, along with the synthesis of the putative structure of (+/-)-Streptoglyceride C. The unique tricyclic ring present in these natural products has been constructed by employing a gold-catalyzed tandem diynol cycloisomerization followed by one-pot dihydroxylation/trans-glycosylation. The pendant diene unit was fabricated by Takai olefination and subsequent Stille coupling. |
| DOI | 10.1021/acs.orglett.5c00879 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.6 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)