Three in one: triple G-C-T base-coded brahma nucleobase amino acid: synthesis, peptide formation, and structural features
Title | Three in one: triple G-C-T base-coded brahma nucleobase amino acid: synthesis, peptide formation, and structural features |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Wagh, MA, Maity, R, Bhosale, RJ, Semwal, D, Tothadi, S, Vaidhyanathan, R, Sanjayan, GJ |
Journal | Journal of Organic Chemistry |
Volume | 86 |
Issue | 21 |
Pagination | 15689-15694 |
Date Published | NOV |
Type of Article | Article |
ISSN | 0022-3263 |
Abstract | This note reports the synthesis and peptide formation of a novel triple G-C-T nucleobase amino acid (NBA) building block featuring three recognition faces: DDA (G mimic), DAA (C mimic), and ADA (T mimic). Readily obtainable in multigram scale in a remarkably easy one-step reaction, this unique NBA building block offers scope for wide ranging applications for nucleic acid recognition and nucleic acid peptide/protein interaction studies. |
DOI | 10.1021/acs.joc.1c01228 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 4.354 |
Divison category:
Organic Chemistry
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