Tf2NH catalyzed 1,6-conjugate addition of 2-hydroxy-p-quinone methides with -functionalized ketones: access to 2,3,4,9-Tetrahydro-1H-xanthenones and 4H-Chromene Derivatives
| Title | Tf2NH catalyzed 1,6-conjugate addition of 2-hydroxy-p-quinone methides with -functionalized ketones: access to 2,3,4,9-Tetrahydro-1H-xanthenones and 4H-Chromene Derivatives |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Satbhaiya, S, Khonde, NS, Rathod, J, Gonnade, R, Kumar, P |
| Journal | European Journal of Organic Chemistry |
| Issue | 20 |
| Pagination | 3127-3133 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 1434-193X |
| Keywords | -Functionalized ketone, 1, 6-Conjugated addition, Bronsted acid, Chromenes, Xanthenones |
| Abstract | A Bronsted acid catalyzed tandem 1,6-conjugate sequential cycloaddition reaction using 2-hydroxy-p-quinone methides and -functionalized ketones is reported. The method allows xanthenones and chromenes to be accessed in moderate to excellent yield with broad substrate scope, which could be further functionalized to give a versatile set of products. |
| DOI | 10.1002/ejoc.201900370 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.029 |
Divison category:
Organic Chemistry
Physical and Materials Chemistry