Tethered aminohydroxylation route to L-arabino-[2R,3S,4R] and L-xylo-[2R,3S,4S]-C-18-phytosphingosines
| Title | Tethered aminohydroxylation route to L-arabino-[2R,3S,4R] and L-xylo-[2R,3S,4S]-C-18-phytosphingosines |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Dubey, A, Kumar, P |
| Journal | Tetrahedron Letters |
| Volume | 50 |
| Issue | 26 |
| Pagination | 3425-3427 |
| Date Published | JUL |
| ISSN | 0040-4039 |
| Keywords | Phytosphingosine, Regioselectivity, Sharpless asymmetric kinetic resolution, Sphingolipids, stereoselectivity, Tethered aminohydroxylation |
| Abstract | A concise and highly efficient synthesis of L-arabino-[2R,3S,4R] and L-xylo-[ 2R,3S,4S]-C-18-phytosphingosines has been achieved. The synthetic strategy features the Sharpless kinetic resolution and tethered aminohydroxylation as the key steps. (C) 2009 Elsevier Ltd, All rights reserved. |
| DOI | 10.1016/j.tetlet.2009.02.173 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry