Synthetic studies toward macrocidins: an RCM approach for the construction of the central cyclic core

TitleSynthetic studies toward macrocidins: an RCM approach for the construction of the central cyclic core
Publication TypeJournal Article
Year of Publication2006
AuthorsRamana, CV, Mondal, MA, Puranik, VG, Gurjar, MK
JournalTetrahedron Letters
Volume47
Issue24
Pagination4061-4064
Date PublishedJUN
Type of ArticleArticle
ISSN0040-4039
Keywordsacyltetramic acid, Lacey-Dieckmann cyclization, macrocidins, Ring closing metathesis
Abstract

The central macrocyclic core of the macrocidins was constructed using RCM as the key reaction. A preliminary investigation dealing with the key reactions, that is, the Dieckmann cyclization and the RCM, revealed that RCM of the beta-ketoamide is better than RCM of the corresponding acyltetramic acid. (c) 2006 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2006.03.192
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.347
Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry
Physical and Materials Chemistry