Synthesis of (R)-selegiline via hydrolytic kinetic resolution

TitleSynthesis of (R)-selegiline via hydrolytic kinetic resolution
Publication TypeJournal Article
Year of Publication2011
AuthorsKondekar, NB, Kumar, P
JournalSynthetic Communications
Volume41
Issue9
PaginationPII 935777980
Date PublishedMAR
ISSN0039-7911
KeywordsCobalt-based chiral salen complex, Hydrolytic kinetic resolution, MAO inhibitors, phenyl propylene oxide, selegiline
Abstract

[image omitted] A short and enantioselective formal synthesis of (R)-selegiline has been achieved using Jacobsen's hydrolytic kinetic resolution (HKR) of phenyl propylene oxide.

DOI10.1080/00397911.2010.481751
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)1.062
Divison category: 
Organic Chemistry