Synthesis of optically pure 2,3,4-trisubstituted tetrahydrofurans via a two-step sequential Michael-Evans aldol cyclization strategy: total synthesis of (+)-magnolone
| Title | Synthesis of optically pure 2,3,4-trisubstituted tetrahydrofurans via a two-step sequential Michael-Evans aldol cyclization strategy: total synthesis of (+)-magnolone |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Pandey, G, Luckorse, S, Budakoti, A, Puranik, VG |
| Journal | Tetrahedron Letters |
| Volume | 51 |
| Issue | 22 |
| Pagination | 2975-2978 |
| Date Published | JUN |
| ISSN | 0040-4039 |
| Keywords | HWE reaction, Lignans, Magnolone, Michael-Evans aldol reaction, Tetrahydrofuran |
| Abstract | Synthesis of optically pure 2,3,4-trisubstituted tetrahydrofurans is described employing a two-step Michael-Evans aldol cyclization strategy. The approach is successfully applied for the total synthesis of furano lignan natural product (+)-magnolone. (C) 2010 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2010.03.111 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry